Monday Night Football odds, predictions, line, time, spread: 49ers vs. Lions picks by NFL expert on 27-6 run



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The Detroit Lions will try to become the first team since 2020 to go 8-0 on the road when they take on the San Francisco 49ers on Monday Night Football. The last team to accomplish that was the 2020 Kansas City Chiefs, who went 14-2 overall. The Lions (13-2), who have set a franchise record for wins, defeated the Chicago Bears, 34-17, in Week 16. The 49ers (6-9), who are fourth in the NFC West, dropped a 29-17 decision to the Miami Dolphins last week. The latest 49ers vs. Lions forecast is calling for partly cloudy skies, light winds, and temperatures around 50. Lions running back David Montgomery is out with a knee injury.

Kickoff from Levi’s Stadium in Santa Clara, Calif., is set for 8:15 p.m. ET. Detroit is a 3.5-point favorite in the latest 49ers vs. Lions odds via SportsLine Consensus, while the over/under for total points scored is 50.5. Before making any 49ers vs. Lions picks, make sure to check out the NFL predictions and betting advice from the SportsLine expert Micah Roberts, considering his mastery of picks involving San Francisco.

Micah Roberts has worked in the Las Vegas sportsbook industry for 20-plus years, including a 13-year run as Station Casinos’ book director. Armed with an elaborate network of sources, Roberts has unmatched info in multiple sports and he’s on an amazing 27-6 (+2038) on his last 33 NFL picks involving the 49ers. Anyone following at sportsbooks and on betting apps has seen huge returns.

Now, Roberts has locked in on Lions vs. 49ers and just revealed his coveted NFL picks and predictions. You can head to SportsLine now to see his picks. Here are several NFL odds and NFL betting lines for 49ers vs. Lions:

  • 49ers vs. Lions spread: Detroit -3.5
  • 49ers vs. Lions over/under: 50.5 points
  • 49ers vs. Lions money line: Detroit -194, San Francisco +161
  • DET: Lions have hit the money line in 17 of their last 21 games (+13.90 units)
  • SF: 49ers have hit the team total under in 16 of their last 22 games (+10.15 units)
  • 49ers vs. Lions picks: See picks at SportsLine
  • 49ers vs. Lions streaming: FuboTV (Try for free)

Why the Lions can cover

Detroit has been led by veteran quarterback Jared Goff. In 15 starts, he has completed 337 of 472 passes (71.4%) for 4,095 yards and 33 touchdowns with 10 interceptions and a rating of 112.2. In the Week 16 win over Chicago, he completed 23 of 32 passes (71.9%) for 336 yards and three touchdowns. He was 38 of 59 (64.4%) for 494 yards and five touchdowns in a 48-42 loss to the Buffalo Bills on Dec. 15.

Second-year running back Jahmyr Gibbs is the Lions’ top rusher. In 15 games, he has carried 209 times for 1,156 yards (5.5 average) and 12 touchdowns. He has had nine explosive plays of 20 yards or more, including a long of 70, and has converted 57 first downs. In the win at Chicago, he carried 23 times for 109 yards (4.7 average) and one touchdown. See who to back at SportsLine.

Why the 49ers can cover

Quarterback Brock Purdy powers the San Francisco attack. In 14 games, he has completed 65% of his passes for 3,487 yards and 17 touchdowns with 10 interceptions and a rating of 94.4. He also has carried 63 times for 311 yards (4.9 average) and four touchdowns. In the loss at Miami, he completed 26 of 40 passes (65%) for 313 yards and two touchdowns with one interception.

His top target is veteran tight end George Kittle. In 13 games, he has caught 68 passes for 967 yards (14.2 average) and eight touchdowns with 456 yards after the catch and 44 first-down conversions. He has had eight explosive plays of 20 yards or more, including a long of 43. See who to back at SportsLine.

How to make 49ers vs. Lions picks

Roberts has analyzed Lions vs. 49ers from every possible angle, and while we can tell you he’s leaning under the total, he has also discovered a critical X-factor that has him jumping all over one side of the spread. Find out what it is, and which team to back, at SportsLine. 

So who wins Lions vs. 49ers on Monday Night Football, and what critical x-factor makes one side of the spread hit hard? Visit SportsLine now to see which side of the Lions vs. 49ers spread to back, all from the expert who is an amazing 27-6 on picks involving the San Francisco 49ers, and find out.





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